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Gluten is a combination of two storage proteins, glutenin and gliadin, that are found in the middle layer, or endosperm, of various cereal grains. Normally, the pancreas secretes digestive enzymes, like proteases and peptidases, to help break down proteins like gluten. However, imbalances in gut bacteria and the normal aging process can limit the body’s natural ability to produce these necessary digestive enzymes.